5 Surprising Things That Spike Blood Sugar (Besides Food!) | NHS Doctor Explains (2026)

Exercise, stress, sleep, infections, and hormones: these are just a few of the surprising factors that can spike blood sugar levels, according to NHS doctor and media personality Dr. Amir Khan. While food is often the first thing that comes to mind when thinking about blood sugar spikes, Dr. Khan highlights that everyday factors can also play a significant role in glucose regulation. In this article, I'll delve into each of these factors, exploring their impact on blood sugar and offering insights into why they matter and how they connect to larger trends in health and wellness.

One thing that immediately stands out is the impact of stress on blood sugar. When we're stressed, our bodies release cortisol, the 'fight or flight' hormone that signals the liver to release stored glucose into the bloodstream. This provides a quick boost of energy, but it can also lead to temporary spikes in blood sugar levels. Chronic stress, however, can lead to chronic glucose spikes, which are not good for long-term health. In my opinion, this highlights the importance of stress management techniques, such as mindfulness and meditation, in maintaining stable blood sugar levels.

Another surprising factor is the impact of poor sleep on blood sugar. Even a single night of poor sleep can increase insulin resistance, leading to elevated blood sugar levels. Chronic sleep deprivation can significantly raise the risk of developing type 2 diabetes, even in people who maintain a healthy diet. This raises a deeper question: how can we improve sleep quality and quantity to support better blood sugar regulation? In my view, this underscores the importance of prioritizing sleep as a fundamental aspect of overall health and wellness.

Exercise is another factor that can temporarily spike blood sugar levels, but it's not all bad news. Certain forms of physical activity, particularly intense or resistance training, can prompt the body to release more glucose into the bloodstream to fuel the muscles. However, regular exercise ultimately improves insulin sensitivity over time, helping the body regulate blood sugar more effectively. This is why I believe that incorporating regular exercise into our daily routines is essential for maintaining stable blood sugar levels and overall health.

Infections and illness are yet another surprising factor that can impact blood sugar levels. When the body is fighting off an infection, it releases more glucose into the bloodstream to help fuel the immune system. This is why people with diabetes often notice higher blood sugar levels when they are unwell. However, this response is completely normal as the body works to combat illness. It's important to note that this highlights the interconnectedness of our body's systems and the need for a holistic approach to health and wellness.

Finally, hormones play a significant role in blood sugar regulation. Fluctuations in hormones during different phases of the menstrual cycle can influence blood sugar levels, with higher progesterone during the luteal phase making cells more insulin resistant. Declining oestrogen levels during perimenopause and menopause can further reduce insulin sensitivity, affecting how the body regulates glucose. This is why women in their 40s and 50s may notice weight gain, fatigue, or brain fog, which can be linked to blood sugar shifts. From my perspective, this highlights the importance of understanding and managing hormonal changes as a key aspect of maintaining stable blood sugar levels and overall health.

In conclusion, blood sugar regulation is a complex and multifaceted process that is influenced by a wide range of factors, from stress and sleep to exercise and hormones. By understanding these factors and their impact on blood sugar, we can take a more holistic approach to health and wellness, incorporating stress management, sleep improvement, regular exercise, and hormonal awareness into our daily routines. In my opinion, this is the key to maintaining stable blood sugar levels and overall health, and it's an area that deserves more attention and research in the field of medicine and wellness.

5 Surprising Things That Spike Blood Sugar (Besides Food!) | NHS Doctor Explains (2026)
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